SportLogia
Vol. 9, Issue 1, Jun 2013.

 

UČESTALOST ANAEROBNE MOĆI KOD BRAZILACA NA
OSNOVU DERMATOGLIFIKE I R577X POLIMORFIZIMA ACTN3 PROTEINA

 

Carlos Renato Paz1,3,6, Ramon Cunha Montenegro1,2,3, Eric de Lucena Barbosa1,2,6,
Asdrúbal Nóbrega Montenegro-Neto2, Sérgio Marques de Lucena4,
Vanduir Soares de Araújo Filho2,4,6, Paula Roquetti Fernandes5,6 i José Fernandes Filho1,5,6
1Autonomni univerzitet Asuncion, Asuncion, Paragvaj
2Labratorija za procjenu fizičkih sposobnosti -  UNIPÊ – SANNY, João Pessoa, Paraíba, Brazil
3Savezni institut za obrazovanje, nauku i tehnoligiju u Paraibu - IFPB, João Pessoa, Paraíba, Brazil
4Policijski naučni institut u Paraibu SPI-OB, João Pessoa, Paraíba, Brazil
5Centar za procjenu vrhunskih fizičkih kvaliteta, Rio de Žaneiro, Brazil
6LABIMH-UFRJ - Istraživačka grupa, Rio de Žaneiro, Brazil

 

PREGLEDNI ČLANAK
doi: 10.5550/sgia.130901.se.006P
UDK: 796.012.1:159.928.23-05(=436)

 

Sažetak   PUNI TEKST(.pdf)

Dermatoglifika i analize Alfa-aktin gena su evluativni instrumenti koji se često koriste za selekciju sportista i uopšte populacije u odnosu na motoričke vještine. Ovo istraživanje imalo je za cilj da utvrdi, na osnovu dermatoglifskih karakteristika i R577X polimorfizma Alfa-aktina, procenat ljudi u saveznoj brazilskoj državi Paraiba sa nepovoljnim sposobnostima za sportove koje karakterišu anaerobne sposobnosti. Izvršena je deskriptivna studija profila sa eks post fakto tipologijom. Identifikovani su dermatoglifski otisci prstiju 309 osoba (149 muškaraca i 160 žena), a ACTN3 genotip je analiziran na njih 96 (40 muškaraca i 56 žena). Dermatoglifski podaci pokazuju da 5,8% populacije obuhvaćene istraživanjem odgovara anaerobnim predispozicijima mišićne moći, dok 94,2% nema te sposobnosti. Genetička analiza frekvencija ukazala je na činjenicu da su 19,8% ispitanika imali XX mutan genotip. Ovi rezultati predstavljaju značajano smanjenje greške u izboru sportista za potencijalno vrhunske rezultate pogotovu u onim sportovima koji zahtijevaju AMP.

 

Ključne riječi: Alpha-actinin, Fingerprint, Genetic Polymorphism, Skeletal Muscle, Genotype frequency.

 

Literatura

Abramova, T. F., Nikitina, T. M., & Ozolin, N. N. (1996). Dermatoglyphic prints. genetic markers in the potential energy of man. Moscow Scientific Annals, 3(13).
Berman, Y., & North, K. N. (2010). A gene for speed: The emerging role of α-actinin-3 in muscle metabolism. Physiology, 25, 250–259. doi: 10.1152/physiol.00008.2010; PMid: 20699471
Bogle, A. C., Reed, T., & Norton, J. A. (1994). Within-pair differences in a-b ridge count asymmetry in monozygotic twins: evidence for a placental proximity effect. Hum Hered, 44, 162–168. doi: 10.1159/000154209; PMid: 8039800
Bustamante-Ara, N., Santiago, C., Verde, Z., Yvert, T., Gómez-Gallego, F., Rodríguez-Romo, G., ... Lucia A. (2010). ACE and ACTN3 genes and muscle phenotypes in nonagenarians. Int J Sports Med, 31, 221–224. doi: 10.1055/s-0030-
1247529
; PMid: 20148371
Cummins, H., & Midlo, C. H. (1961). Fingerprints, palms and soles: an introduction to dermatoglyphics. New York: Dover Publications Inc.
Druzhevskaya, A. M., Ahmetov, I. I., Astratenkova, I. V., & Rogozkin, V. A. (2008). Association of the ACTN3 R577X polymorphism with power athlete status in Russians. Eur J Appl Physiol, 103, 631–634. doi: 10.1007/s00421-008-0763-1; PMid: 18470530
Eynon, N., Duarte, J. A., Oliveira, J., Sagiv, M., Yamin, C., Meckel, ... Goldhammer, E. (2009). ACTN3 R577X Polymorphism and Israeli Top-level Athletes. Int J Sports Med, 30, 695–698. doi: 10.1055/s-0029-1220731; PMid: 19544227
Holdys, J., Kryściak, J., Stanisławski, D., & Gronek, P. (2011). Polymorphism of the α-actn3 gene in individuals practising different sports disciplines. Biol Sport, 28, 101–106. doi: 10.5604/942738
Junior, A. T. C., Cunha, A. C. P. T., Scheneider, A. T., & Dantas, P. M. S. (2006). Características dermatoglíficas, somatotípicas, psicológicas e fisiológicas da seleção brasileira feminina adulta de handebol [Features dermatoglyphics, somatotype, psychological and physiological of the Brazilian adult female handball]. Fit Perf J., 5, 81–86. doi: 10.3900/fpj.5.2.81.p
Kansal, D. K. (2010). A critical study of sports talent selection and promotion of sports participation, at young age. Br J Sports Med, 44, i65–i66. doi: 10.1136/bjsm.2010.078725.219
Klein, C. M. O., & Fernandes-Filho, J. (2003). Relação entre a dermatoglifia, as qualidades físicas e o nível maturacional de escolares adolescentes de ambos os sexos. Fit Perf J, 2, 321–329.
Kücken, M., & Newell A. C. (2005). Fingerprint formation. J Theor Biol, 235, 71–83. doi: 10.1016/j.jtbi.2004.12.020; PMid: 15833314
Linhares, R. V., Matta, M. O., Lima, J. R. P., Dantas, P. M. S., Costa, M. B., Fernandes Filho, J. (2009). Efeitos da maturação sexual na composição corporal, nos dermatóglifos, no somatótipo e nas qualidades físicas básicas de adolescentes [Efeitos da maturação sexual na composição corporal, nos dermatóglifos, no somatótipo e nas qualidades físicas básicas de adolescentes]. Arq Bras Endocrinol Metab, 53, 47–54. doi: 10.1590/S0004-27302009000100008; PMid: 19347185
Macêdo, M. M., & Fernandes-Filho, J. (2003). Estudo das características dermatoglíficas, somatotípicas e das qualidades físicas básicas nos diversos estágios de maturação sexual [Study of dermatoglyphic characteristics, somatotype and basic physical qualities in different stages of sexual maturation]. Fit Perf J, 2, 315–320.
doi: 10.3900/fpj.2.6.315.s; doi: 10.3900/fpj.2.6.315.p
McCauley, T., Mastana, S. S., & Folland, J. P. (2010). ACE I/D and ACTN3 R/X polymorphisms and muscle function and muscularity of older Caucasian men. Eur J Appl Physiol, 109, 269–277. doi: 10.1007/s00421-009-1340-y; PMid: 20069311
Mills, M. A., Yang, N., Weinberger, R. P., Vander Woude, D. L., Beggs, A. H., ... North, K. N. (2001). Differential expression of the actin-binding proteins, α-actinin-2 and -3, in different species: implications for the evolution of functional redundancy. Hum Mol Genet, 10, 1335–1346. doi: 10.1093/hmg/10.13.1335; PMid: 11440986
Moran, C. N., Yang, N., Bailey, M. E. S., Tsiokanos, A., Jamurtas, A., MacArthur, D. G., ... Wilson, R. H. (2007). Association analysis of the ACTN3 R577X polymorphism and complex quantitative body composition and performance phenotypes in adolescent Greeks. Eur J Hum Genet, 15, 88–93. doi: 10.1038/sj.ejhg.5201724; PMid: 17033684
Niemi, A. K., & Majamaa, K. (2005). Mitochondrial DNA and ACTN3 genotypes in Finnish elite endurance and sprint athletes. Eur J Hum Genet, 13, 965–969. doi: 10.1038/sj.ejhg.5201438; PMid: 15886711
Norman, B., Esbjörnsson, M., Rundqvist, H., Österlund, T., von Walden, F., & Tesch, P. A. (2009). Strength, power, fiber types, and mRNA expression in trained men and women with different ACTN3 R577X genotypes. J Appl Physiol, 106, 959–965. doi: 10.1152/japplphysiol.91435.2008; PMid: 19150855
North, K. N., Yang, N., Wattanasirichaigoon, D., Mills, M., Easteal, S., & Beggs, A. H. (1999). A common nonsense mutation results in alpha-actinin-3 deficiency in the general population. Nat Genet, 21, 353–354. doi: 10.1038/7675; PMid: 10192379
Papadimitriou, I. D., Papadopoulos, C., Kouvatsi, A., & Triantaphyllidis, C. (2008). The ACTN3 gene in elite Greek track and field athletes. Int J Sports Med, 29, 352–355. doi: 10.1055/s-2007-965339; PMid: 17879893
Roth, S. M., Walsh, S., Liu, D., Metter, E. J., Ferrucci, L., & Hurley, B. F. (2008). The ACTN3 R577X nonsense allele is underrepresented in elite-level strength athletes. Eur J Hum Genet, 16, 391–394. doi: 10.1038/sj.ejhg.5201964; PMid: 18043716; PMCid: 2668151
Ruiz, J. R., Arteta, D., Buxens, A., Artieda, M., Gómez-Gallego, F., Santiago, C., ... Lucia, A. (2010). Can we identify a power-oriented polygenic profile? J Appl Physiol, 108, 561–566. doi: 10.1152/japplphysiol.01242.2009; PMid: 20044471
Ruiz, J. R., del Valle, M. F., Verde, Z., Díez-Veja, I., Santiago, C., Yvert, T., ... Lucia, A. (2011). ACTN3 R577X polymorphism does not influence explosive leg muscle power in elite volleyball players. Scand J Med Sci Sports, 21, e34–41. doi: 10.1111/j.1600-0838.2010.01134.x; PMid:0561285
Scott, R. A., Irving, R., Irwin, l., Morrison, E., Charlton, V., Austin, K., ... Pitsiladis, Y. P. (2009). ACTN3 and ACE genotypes in elite Jamaican and US sprinters. Med Sci Sports Exerc, 42, 107–112.
doi: 10.1249/MSS.0b013e3181ae2bc0; PMid: 20010124
Walsh, P. S., Metzger, D. A., & Higuchi, R. (1991). Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material. Biotechniques, 10, 506–513. PMid: 1867860
Yang, N., MacArthur, D. G., Gulbin, J. P., Hahn, A. G., Beggs, A. H., Easteal, S., & North, K. (2003). ACTN3 genotype is associated with human elite athletic performance. Am J Hum Genet, 73, 627–631. doi: 10.1086/377590; PMid: 12879365; PMCid: 1180686
Zary, J. C. F., & Fernandes-Filho, J. (2007). Identificação do Perfil Dermatoglífico e Somatotípico dos Atletas de voleibol masculino adulto, juvenil e infanto-juvenil, de alto rendimento no Brasil [Identification and Profile Dermatoglyphic somatotypical Athletes volleyball adult male, juvenile and juvenile, high yield in Brazil]. R bras Ci e Mov, 15, 53–60.
Zary, J. C., Reis, V. M., Rouboa, A., Silva, A. J., Fernandes, P. R., & Fernandes Filho, J. (2010). The somatotype and dermatoglyphic profiles of adult, junior and juvenile male Brazilian top-level volleyball players. Sci Sports, 25, 146–152. doi: 10.1016/j.scispo.2009.09.002
Zempo, H., Tanabe, K., Murakami, H., Iemitsu, M., Maeda, S., & Kuno, S. (2010). ACTN3 Polymorphism Affects Thigh Muscle Area. Int J Sports Med, 31, 138–142. doi: 10.1055/s-0029-1242808; PMid: 20222007